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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd489c3971705657c24cb35780b1451da3fc5cbd1c51557fce56417c55b0b3f53' 
  AND token = 'T9Y32XzjvnVtNRlxC16BKW9948xqi5Z1iInI+Gz4mKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}