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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c5caf1b8c2ebfbac26af137ca011fd67a0380798dfe1dac2a1abdf7a653228' 
  AND token = 'gCLgm8Q4AKNIbKf3Bl61OqF8MD5RKxN7TFuDn0UqIO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}