SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '622aa01fde1b80c3a9f46d1a375d79c4959525186d4f0c852d3b3abb32c238c3' 
  AND token = 'A8o+aOOHH/ylNsJMGXzTb9F7KNBm87QhwfvDAosAOlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}