SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00bc7a5ddc034ddbe01fb137f758807feda483f299af1f9ac6d2d2f1f764d479' 
  AND token = 'zFm+hinvNY/pVzfy/z2ULyVrA6FDo8Pw9blA+sZZ//4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}