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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad27a80968314d1ff9193f97fba1465dff8d2e39cfa2e6234779a840b335d60' 
  AND token = 'Viw2MUb9L6nQ7BdR0T2AqfWHJWoHltH6UdXx6tICsOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}