SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49fc9ab6432b8a189d4d2ce18a60abf6dfb22709ba23d68bea4e892d9e532090' 
  AND token = 'mLzjHYohlZABYEt1QYSs9TyMRgIUXaawpZ1fHQoRfKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}