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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d64a055cb20b35e7b65d99c4f74a55d3cf0a7fff37893d72aa817e5c8f7d68e' 
  AND token = 'O4B8X1qiRedAuKv4iPsqk7AwN/HLFrRjX4ZDMrHu7tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}