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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '003258a8f7d58221dd6a49483c0a6d5f8599939542951db98ce301f6738f6b3f' 
  AND token = 'RhRx1/+HAmL8WE4u0PEcLW4NJHw43D/kUnbW+cqGkVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}