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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cce25e12d5b99e3b5e1ab079f97a1531bd189bdca3a66a83a28a3dcb8643fda1' 
  AND token = 'u6HMzwX4mkeqnToH0sCQ2S0K7ri9e5lcF4u0AUM2dSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}