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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e23eff4486ddc47e8132751389f7f8af9b568da80a6a0c84bbe3cf54e40b8558' 
  AND token = 'Ecp0j+OQncqlfHZpg3N40Icg1w73iI3bjlF5RQ3oHiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}