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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6484e2e5ef6b98156ad7f15818b8891059c22686c696a8fc85a3c34a2d4fdaa' 
  AND token = 'x1Kgd9xG8vFawTH4oaUo7IU8OfXR1aqgJcWoZOo36wY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}