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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8c4c2dd96b2846d693ab1a06733434a5b09439fd9d417293a7e1172ae3c2e38' 
  AND token = 'PeSA78yZsM7fQuzu5VihLq62RtxLnmNAEHY1dVN8SeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}