SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14e3c5999034f91cee36f7644e917ed9c65c7e172636166de42cdbec71a24f42' 
  AND token = 'fSyY9g6YPcPEDzG3cdb1Adt3Bykb6uikZ2mqT4J4qSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}