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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '220005af8dcb93b250c4850aece9f536f50f64520c81843b4d8cc7ff867360b5' 
  AND token = '1YGGrMbcy+lUlI2Jo+oe2lYF52EtTx8N3Gs/QFL1JH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}