SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '829a3281c52cde3279e23d5a8e7e6e58006b97f798a0f682f6cc546b27767f29' 
  AND token = 'hWMMaNt4VzZq64AS3bKd9TXcuMNYZFaFvzC51e/uz/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}