SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd514000a24bf4129b6aff3bed480392eeac44a04922fa245b6eb2bb0ba2b5558' 
  AND token = 'LnRMv7CY/0eENgDZeN0bTw8qyZHCOWQLyZrBNhSMWE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}