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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca5227b369409264449a1b5f9e72e4d685d3a7d1501da5ca89f281c4d58289b9' 
  AND token = '2hUSxzY0yxM/fspGd5y7t+RUUCwC5Ro7b64c48+EU1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}