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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eaefe417dc84ab4d0aa337fa16738f502b7d8908a9d7de17b82cbcf9039ba6f' 
  AND token = 'I/O/PG4uQZeixhIjwLnsNIKPoYO66apJ3lYxuo3R3zU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}