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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5a50f59906da5210fa9d95d0f6a149fa1294b15dbab90908bc9164c8f6830e4' 
  AND token = 'XRdpYtDKHa1hpYP+pYLeN2QoNZ2Np67dmczIOZAyVu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}