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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4270dda93ff8be7eb8e868ceb1e95fd0adef60885814f0ffbed378563654ef22' 
  AND token = '34tzE5grWjtoYRaffxo/g1XWlJvNjXfO8iDa+It9dmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}