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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0449be8f45e31d3056b71ac731e1da2b90b94ed88b0f549daca47d307ca25d9' 
  AND token = 'PM75z2ZfJoQ5CSiPFW0omuZ9CV2TIQB5nmqURWiuHJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}