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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1605e42793ded3f0a3ecc57c2aea1f876d12c4c601bedd6ed3103dc7766bc99' 
  AND token = 'Lf/T4TuOTpggRkUZeTVbDmvrdYiOZR8BbooJ7T4LiNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}