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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5119dd478aa76370cd2003a4a9c30f9817408e345bb6cdc9c8895dc010bd32a8' 
  AND token = 'a+k/lyl+MdqhaeUHBHijQs1sT+h/8JeWXjakS8g4rMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}