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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5df67efdd4b652c65f8b9777d91805e51e297023531e875f6d2697a8c3a31754' 
  AND token = '7CVp9JFw9C5rK3PtQxZIknUm3xaPOjsIDyDYxixyjiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}