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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7d20b65d431bdf52b18f65ad4879567c1c55a2f398508b002157a0e1d8cdfd6' 
  AND token = '5L/406xfOQ1eoVQZTlukd7uP0mTacwewkiIJ8Pf/nls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}