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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd1288d26292de29d278528ecf3e04de32c5dce52dfa34fda2cdc96e76072ccd' 
  AND token = 'ziO81xDzJ5cDR/vq1j7zEb0WyYoFJNv0BaHQ2IVcxQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}