SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b50c6b4dce9c3e33d87809f67de64100d34b5021c2a02a2567a803953817628' 
  AND token = 'ZKu1fuhkKKASPCPkGiq0aRz+poRw4o4mVrfqNdM8A7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}