SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eceb1d23886468bdc680bb61a2ad7880279ad66445129adc796024e4b616ec4' 
  AND token = 'dFgHuJWdr7Pxl/aRgBhvV9pXivi7XXonTsgPsehiH88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}