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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8488e613745e296449555bd2ff1ded5e1510e8522dc2950306e53a0423f235bc' 
  AND token = 'xXzK8IYNqO1IN+5uMjUWzwv3+pwB01Pw+441mPy0elI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}