SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37fbb7bd1da16a6ea3d530ec415faaec977d9fa16cfaf051bb8696cf9c0158f7' 
  AND token = '6xEax89mYz+gqHJC81NGwa34DJHVau4IsbcDNOXqZzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}