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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e00e2236cc0be9218cb3c0fb28a2e4d6cd3f348d443c735580a88accb2f8b65a' 
  AND token = 'PNCax/XOvS0ODaCL8yIk5e8u9qyRq5KquNyo9XquVr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}