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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3003afd90695d5530d5244aaca9f80b9e412f65b5fea92a0eddf143e82a16aff' 
  AND token = 'RUcU6tz3UPilRupNKFhU5tHx5uAW24QOBwBRH7YgGtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}