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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e253c37c74a591e5c87c4b39b283ccbf4f68784c3ee9c1b53eb8bfdc6b8c66' 
  AND token = '1bMFsw6uPHb+Y5QysANY0UbsNcW1pBqR7c6A+Cu16Lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}