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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73e74bf283b2f41c904d502495205a328e1c60a906686e048df1a00bd9cf203f' 
  AND token = 'KsUHYEzY6gtnlHwy00bimw9wQAdsQHXk9DHR0+siUkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}