SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e41f34548b5e23ef18de25258639144f2bef855a3f4505a62b7059238f05bd6' 
  AND token = 'rdTVYge3EAy58g6tL1P7iyOcNg1N2BPI3K5gKa9KxmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}