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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b20025eaf8cfd9798d5336e6575a2555b37cbfffa061e13861ec2e7d7ec88a4' 
  AND token = 'YrmviSqmVsQ3vh8bcOeUrlXR/PmDUoaY6iWeXxISgE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}