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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a8ccc59bdcc170326598bc6272e52b00a4af9250a038e317a857a1732f1c76f' 
  AND token = 'WD+khrWJxZ/fGbQ3Qj/eJVl/fcwJICwIy7iTTnZBri0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}