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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e063f24dd601556b1e04c15c050e65a6355a3488f93c95705393345fe9b78466' 
  AND token = '5+FSRGZyYSYJCzAiu+dC4U3zxAvRF6DTUsO+N9Ky1dY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}