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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86e70734f63e6bddf9aff047c28b72f1ac58d80d274180c416b8ffe028162531' 
  AND token = 'BhVYJlyt1NDRlUIZoV40UqAR2FfTrUVFB2+yQ0V1/uY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}