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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '356dee55bf1c41a5429e50627cd064127f032994cd973378748049d865f542c7' 
  AND token = '+FJ2a1c0FrURgejuNHORSRbf6TpjeueJOj2f9zj27e4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}