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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a11a7b0a3c02edd317fed8da326a5b78d65d76e432a5bd8798b924379c375ef' 
  AND token = 'wdx1X0aF4nncDbiLri+i4FXAZCXoq8UrBKLn857BuIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}