SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ec71bfeb637c26f441c72fc307851b92cd53b797de8c81a1c4d948c2b27cc9' 
  AND token = 'PzQ8suNq8HOocoYSTNeV86fPD0yTrlC9x+Q4aq1fD2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}