SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9327d8e792994d12d4d489862ea69220c3000dc4a34f6cb643590e66097ae20a' 
  AND token = 'rRttE1MLbQzIbIN6l8CT64X3Aw0DtSTEw+cyIiV+dNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}