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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48301f953e06f099114516721ed6056b049b6e10966f30c6cb061ef9490c0fa9' 
  AND token = 'JFDrcHZbpillfkUGqoeJqH0V110tBaCKa/K2PJqazjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}