SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0559a9cd46529417115de378df5e26314e91eb8ac053f2f924542954ac6cffad' 
  AND token = 'Poy4kyalUmwWYf4bxNcPl+oRL+YkDs9xB3+mgSxy/rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}