SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a66d9b5c5bc022219ba9e2195b98b629ae791aeebfd517b2fd322b3b7a91622' 
  AND token = 'zpqHMxUNryU+SHJ6KfBXYY38HcIrBWmW1/V0KE8SXKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}