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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a1357faa354197f5a2ef7b9668c71e9927c4493bd7725018396a82227154ec0' 
  AND token = 'FEe4glNDPv28q4MKrJfYY35O8KoW51InA9mshqn4WbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}