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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '798aec6cc45f2472569bfa242fae00d6bb8fba099d723bb0a6a346751848a524' 
  AND token = 'Kx2mLoj1R8X8Vc4Bo5A8QUK93rHMLw6LVgndy/G8DGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}