SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a59beebf93e06879f66bf2e2f05755688aaa78a28b9054808b0422749aeac050' 
  AND token = 'zgt86OgJRPYT+k9OWHgryFEYBSYCqFAARzOnmiHtd8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}