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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '104ed24f396462c8f5ad202d47af925b8f7d45ccd027848722a5fbcb50f83169' 
  AND token = 'FRr4NhUTNf3dwXz620R8JFWveviOgK1aZ6/056kYihk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00085

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}